Eb and Zeb are introduced as a simple America characters from a small town unchanged by modern times. Written by John Hasty, Eb and Zeb is a comedy about two old friends "Zeb tall and angular and Eb short and fat" who run a general store in Corn Center. Not only is Eb short and fat, but his mouth makes a whistle sound when he talks.

They are simple men and most of the plotlines are about by interesting people that come into their store, fixing problems in the store, or promotion ideas such as painting a sign. Much of the show's humor is derived from Eb and Zeb's slow minds and silly business ideas. The Shell Oil Company sponsors the show.